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humanized antibodies

См. также в других словарях:

  • Humanized antibody — Humanized antibodies or chimeric antibodies are a type of monoclonal antibody that have been synthesized using recombinant DNA technology to circumvent the clinical problem of immune response to foreign antigens. The standard procedure of… …   Wikipedia

  • humanized antibody — Usually a mouse monoclonal antibody directed against a target of particular therapeutic value that has been modified to have all regions except the antigen binding portion substituted by human immunoglobulin domains. The procedure should make the …   Dictionary of molecular biology

  • Nomenclature of monoclonal antibodies — List of stems for monoclonal antibody nomenclature[1][2][3] …   Wikipedia

  • Monoclonal antibodies — A general representation of the methods used to produce monoclonal antibodies. Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique… …   Wikipedia

  • Monoclonal antibody therapy — Each antibody binds only one specific antigen. Monoclonal antibody therapy is the use of monoclonal antibodies (or mAb) to specifically bind to target cells or proteins. This may then stimulate the patient s immune system to attack those cells.… …   Wikipedia

  • Fusion protein — This article is about chimeric fusion proteins. For proteins involved in membrane fusion, see membrane fusion protein. Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes which originally coded for… …   Wikipedia

  • Daclizumab — Masse/Länge Primärstruktur 142,6 kDa …   Deutsch Wikipedia

  • 1986 in science — The year 1986 in science and technology involved many significant events, some listed below.Astronomy and space exploration* January 24 Voyager 2 space probe makes first encounter with Uranus. * January 28 Space Shuttle Challenger explodes on… …   Wikipedia

  • Natalizumab — ? Monoclonal antibody Type Whole antibody Source Humanized (from mouse) Target alpha 4 integrin Clinical data Trade names Tysabri AHFS/ …   Wikipedia

  • Nimotuzumab — ? Monoclonal antibody Type Whole antibody Source Humanized (from mouse) Target EGFR Clinical data Pregnancy cat.  ? Legal status …   Wikipedia

  • Otelixizumab — ? Monoclonal antibody Type Whole antibody Source Chimeric/humanized hybrid (rat/human) Target CD3E Clinical data Pregnancy cat.  ? …   Wikipedia

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